Recombinant Mouse Ribonucleoprotein PTB-binding 1 (Raver1)

中文名稱：

小鼠Raver1重組蛋白
貨號：

CSB-YP880427MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Raver1重組蛋白
貨號：

CSB-EP880427MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Raver1重組蛋白
貨號：

CSB-EP880427MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Raver1重組蛋白
貨號：

CSB-BP880427MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Raver1重組蛋白
貨號：

CSB-MP880427MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Raver1
Uniprot No.：

Q9CW46
別名：

Raver1; Kiaa1978; Ribonucleoprotein PTB-binding 1; Protein raver-1
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-748
氨基酸序列

AADVSVTHR PPLSPEAEAE AETPETVDRR APEQELPPLD PEEIRKRLEH TERQFRNRRK ILIRGLPGDV TNQEVHDLLS DYELKYCFVD KYKGTAFVTL LNGEQAEAAI NTFHQSRLRE RELSVQLQPT DALLCVANLP PSLTQAQFEE LVRPFGSLER CFLVYSERTG HSKGYGFAEY MKKDSAARAK SDLLGKPLGP RTLYVHWTDA GQLTPALLHS RCLCVDHLPP GFSDVDALRR ALSVVYTPTF CQLACGQDGQ LKGFAVLEYE TAEMAEAAQE RADGQALGDS HLRVSFCAPG PPGRSMLAAL IAAQATALNR GKGLLPEPNL LQLLNNLGPS ASLQLLLNPL LHGGASGKQG LLGAPPAMPL LSGPALSTAL LQLALQSQSQ NQSQGQKKPG ILGDSPLGTL QAGAQPSNSL LGELSAGGGL APELPPRRGK PQPLLPPLLG PSGGDREPMG LGPPATQLTP PPAPVGLRGS NHRGLPKDSG PLPTPPGVSL LGEPPKDYRI PLNPYLNLHS LLPSSNLAGK ETRGWGGSGR GRRPAEPPLP SPAVPGGGSG SNNGNKAFQM KSRLLSPIAS NRLPPEPGLP DSYGFDYPTD VGPRRLFSHP REPTLGAHGP SRHKMSPPPS SFNEPRSGGG SGGPLSHFYS GSPTSYFTSG LQAGLKQSHL NKAVGSSPMG SSEGLLGLGP GPNGHSHLLK TPLGGQKRSF SHLLPSPEPS PEGSYVGQHS QGLGGHYADS YLKRKRIF
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA.
基因功能參考文獻：
1. PTB-mediated splicing repression involves recruitment of raver1 as a potent splicing co-repressor. PMID: 14633994
2. In mice, raver1 might link gene expression with structural functions of muscle contractility during muscle differentiation. PMID: 17096167
3. raver1 may play an important role for the regulation of neuronal synaptic plasticity, possibly by controlling especially the late LTP via posttranscriptional mechanisms. PMID: 18061163
亞細胞定位：

Nucleus. Cytoplasm. Note=Nuclear, in perinucleolar structures. Shuttles between nucleus and cytoplasm. Cytoplasm, at focal contacts and cell-cell contacts. Associated with myotubes during muscle differentiation.
組織特異性：

Ubiquitous.
數據庫鏈接：

KEGG: mmu:71766

STRING: 10090.ENSMUSP00000111150

UniGene: Mm.196137