Recombinant Mouse Protein very KIND (Kndc1), partial

中文名稱：

小鼠Kndc1重組蛋白
貨號：

CSB-YP608072MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Kndc1重組蛋白
貨號：

CSB-EP608072MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Kndc1重組蛋白
貨號：

CSB-EP608072MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Kndc1重組蛋白
貨號：

CSB-BP608072MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Kndc1重組蛋白
貨號：

CSB-MP608072MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Kndc1
Uniprot No.：

Q0KK55
別名：

Kndc1; Kiaa1768; Rasgef2; Vkind; Kinase non-catalytic C-lobe domain-containing protein 1; KIND domain-containing protein 1; Protein very KIND; v-KIND; Ras-GEF domain-containing family member 2
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pathway linking RAS and MAP2. May be involved in cellular senescence.
基因功能參考文獻：
1. our results suggest that v-KIND is required for compact dendritic growth and proper excitatory synaptic connections in cerebellar granule cells, which are necessary for normal motor coordination and balance. PMID: 28264072
2. results demonstrate the structural and functional determinant underlying the v-KIND-MAP2 interaction that controls dendrite arborization patterns PMID: 21385318
3. During mouse embryogenesis the VKIND gene was specifically expressed in the developing nervous system. PMID: 16099729
4. v-KIND mediates a signaling pathway that links Ras and MAP2 to control dendrite growth PMID: 17984326
亞細胞定位：

Cell projection, dendrite. Perikaryon.
組織特異性：

Highly expressed in the brain and at low levels in the ovary. In the brain it is most prominently expressed in the cerebellum where it is restricted to the granular Purkinje cell layer.
數(shù)據(jù)庫鏈接：

KEGG: mmu:76484

STRING: 10090.ENSMUSP00000050586

UniGene: Mm.44442