Recombinant Mouse Protein phosphatase 1 regulatory subunit 1A (Ppp1r1a)

中文名稱：

小鼠Ppp1r1a重組蛋白
貨號(hào)：

CSB-YP872135MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Ppp1r1a重組蛋白
貨號(hào)：

CSB-EP872135MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Ppp1r1a重組蛋白
貨號(hào)：

CSB-EP872135MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Ppp1r1a重組蛋白
貨號(hào)：

CSB-BP872135MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Ppp1r1a重組蛋白
貨號(hào)：

CSB-MP872135MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ppp1r1a
Uniprot No.：

Q9ERT9
別名：

Ppp1r1a; Protein phosphatase 1 regulatory subunit 1A; Protein phosphatase inhibitor 1; I-1; IPP-1
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-171
氨基酸序列

MEPDNSPRKI QFTVPLLEPH LDPEAAEQIR RRRPTPATLV LTSDQSSPEI DEDRIPNSLL KSTLSMSPRQ RKKMTRTTPT MKELQTMVEH HLGQQKQGEE PEGATESTGN QESCPPGIPD TGSASRPDTP GTAQKSAESN PKTQEQCGVE PRTEDSSAHM LPLDSQGASL V
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
基因功能參考文獻(xiàn)：
1. I-1 and sarco/endoplasmic reticulum Ca2+ -ATPase synergistically induce the vascular smooth muscle cell contractile phenotype. PMID: 24249716
2. These data indicate a potential role for DARPP-32 and inhibitor-1 in the regulation of PP1 activity in pancreatic beta-cell stimulus-secretion coupling. PMID: 15737638
蛋白家族：

Protein phosphatase inhibitor 1 family
數(shù)據(jù)庫鏈接：

KEGG: mmu:58200

STRING: 10090.ENSMUSP00000023133

UniGene: Mm.143788