Recombinant Mouse Potassium voltage-gated channel subfamily H member 3 (Kcnh3), partial

中文名稱：

小鼠Kcnh3重組蛋白
貨號：

CSB-YP893906MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Kcnh3重組蛋白
貨號：

CSB-EP893906MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Kcnh3重組蛋白
貨號：

CSB-EP893906MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Kcnh3重組蛋白
貨號：

CSB-BP893906MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Kcnh3重組蛋白
貨號：

CSB-MP893906MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Kcnh3
Uniprot No.：

Q9WVJ0
別名：

Kcnh3; Elk2; Potassium voltage-gated channel subfamily H member 3; Ether-a-go-go-like potassium channel 2; ELK channel 2; mElk2; Voltage-gated potassium channel subunit Kv12.2
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current with fast inactivation. Channel properties may be modulated by cAMP and subunit assembly.
基因功能參考文獻：
1. Authors identified ligands of the TGFbeta- and IGF-family, Foxo1, Foxo3 and Kcnh3 as novel FOXG1-target genes during telencephalic development and showed that FOXG1 interferes with Foxo1 and Tgfbeta transcription. PMID: 27224923
2. We found the voltage-gated K+ channel Kv12.2 to be a potent regulator of excitability in hippocampal pyramidal neurons. Genetic deletion and pharmacologic block of Kv12.2 substantially reduced the firing threshold of these neurons. PMID: 20676103
3. Data suggest that only glycosylated Kv12.2 channels (Kcnh3) show proper voltage dependence and are utilized in vivo. PMID: 19808681
亞細胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv12.2/KCNH3 sub-subfamily
組織特異性：

Detected in brain, but not in other tissues.
數據庫鏈接：

KEGG: mmu:16512

STRING: 10090.ENSMUSP00000040548

UniGene: Mm.374793