Recombinant Mouse Mevalonate kinase (Mvk)

中文名稱：

小鼠Mvk重組蛋白
貨號：

CSB-YP015247MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Mvk重組蛋白
貨號：

CSB-EP015247MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Mvk重組蛋白
貨號：

CSB-EP015247MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Mvk重組蛋白
貨號：

CSB-BP015247MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Mvk重組蛋白
貨號：

CSB-MP015247MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Mvk
Uniprot No.：

Q9R008
別名：

Mvk; Mevalonate kinase; MK; EC 2.7.1.36
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-395
氨基酸序列

MLSEALLVSA PGKVILHGEH AVVHGKVALA AALNLRTFLL LRPQSNGKVS VNLPNIGIKQ VWDVGMLQRL DTSFLEQGDV SVPTLEQLEK LKKMGDLPRD RAGNEGMALL AFLYLYLAIC RKQRTLPSLD MVVWSELPPG AGLGSSAAYS VCLAAALLTA CEEVSNPLKD GVSVSRWPEE DLKSINKWAF EGERVIHGNP SGVDNAVSTW GGALRFQQGT MSSLKSLPSL QILLTNTKVP RSTKALVAAV RSRLTKFPEI VAPLLTSIDA ISLECERVLG EMVAAPVPEQ YLVLEELIDM NQHHLNALGV GHNSLDQLCQ VTAAHGLHSK LTGAGGGGCG ITLLKPGLEQ ATVEAAKQAL TSCGFDCWET SIGAPGVSTH SAAAVGDPVR QALGL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
基因功能參考文獻：
1. analyis of the aberrant expression of costimulatory molecules in splenocytes of the mevalonate kinase-deficient mouse model of human hyper-IgD syndrome PMID: 21607759
2. PTH stimulated BMP-2 mRNA expression via the mevalonate pathway and ROK in osteoblastic MC3T3-E1 cells PMID: 19672814
3. a mevalonate kinase (Mvk) allele deletion yields a murine model of hyper-IgD syndrome PMID: 18008182
亞細胞定位：

Cytoplasm. Peroxisome.
蛋白家族：

GHMP kinase family, Mevalonate kinase subfamily
數據庫鏈接：

KEGG: mmu:17855

STRING: 10090.ENSMUSP00000036971

UniGene: Mm.28088