Recombinant Mouse Lysine-specific demethylase 4D (Kdm4d)

中文名稱：

小鼠Kdm4d重組蛋白
貨號：

CSB-YP668857MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Kdm4d重組蛋白
貨號：

CSB-EP668857MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Kdm4d重組蛋白
貨號：

CSB-EP668857MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Kdm4d重組蛋白
貨號：

CSB-BP668857MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Kdm4d重組蛋白
貨號：

CSB-MP668857MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Kdm4d
Uniprot No.：

Q3U2K5
別名：

Kdm4d; Jhdm3d; Jmjd2dLysine-specific demethylase 4D; EC 1.14.11.-; JmjC domain-containing histone demethylation protein 3D; Jumonji domain-containing protein 2D
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-510
氨基酸序列

MKTKSTCAQN PNCSIMIFRP TKEEFNDFDK YIAYMESQGA HRAGLAKVIP PKEWRARQSY DNISNILIAT PLQQVVSGQA GVFTQYHKKK KGMTVGEYRE LANSKKYQTP PHLDFEDLER KYWKNRLYES PIYGADVSGS LFDGKTQQWN VGHLGTIQDL LEQECGIVIE GVNTPYLYFG MWKTTFAWHT EDMDLYSINY LHFGQPKTWY AVPPEHGRRL ERLARELFPG SSQGCQAFLR HKVALISPTV LKENGIPFGR ITQEAGEFMV TFPYGYHAGF NHGFNCAEAI NFATPRWIDY GKVASQCSCG EARVSFSMDA FVRILQPERY ELWKRGQDQA VVDHTETMVS TSQELTTRRV TKAPRKTWGL KRLRLRQVSR SLLPIATVSN VPCNMQVCHT SRQPSDVKGD DVQKSDSARA SPHPLSLPSS GHMSTRRCSL GRRPCELGAQ ESSNGAPVKR QLPAGRDDTS PSPELQPQAV SGDLIVDSGL VNPGPQHLMT ASEGGLTSDP
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
基因功能參考文獻：
1. These results suggest that demethylation of H3K9 in round spermatids is dispensable for spermatogenesis but that possible defects in Kdm4d-null elongating spermatids could be rescued by functional redundancy of the KDM4B demethylase. PMID: 21293030
亞細胞定位：

Nucleus.
蛋白家族：

JHDM3 histone demethylase family
數據庫鏈接：

KEGG: mmu:244694

STRING: 10090.ENSMUSP00000061632

UniGene: Mm.240457