Recombinant Mouse Leucine-rich repeat-containing protein 4 (Lrrc4), partial

中文名稱：

小鼠Lrrc4重組蛋白
貨號：

CSB-YP860416MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Lrrc4重組蛋白
貨號：

CSB-EP860416MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Lrrc4重組蛋白
貨號：

CSB-EP860416MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Lrrc4重組蛋白
貨號：

CSB-BP860416MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Lrrc4重組蛋白
貨號：

CSB-MP860416MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Lrrc4
Uniprot No.：

Q99PH1
別名：

Lrrc4Leucine-rich repeat-containing protein 4; Brain tumor-associated protein MBAG1; Netrin-G2 ligand; NGL-2
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays an important role for auditory synaptic responses. Involved in the suppression of glioma.
基因功能參考文獻：
1. our results identify NGL-2 as a central component of pathway-specific development in the outer retina. PMID: 23864682
2. These results demonstrate that NGL-2 is critical for pathway-specific synapse development and functional integration of distinct inputs. PMID: 23177961
3. LRRC4 may play an important role in maintaining normal function and suppressing tumorigenesis in the central nervous system. PMID: 15967442
4. Together, these findings provide clues to the function of LRRC4 as a negative regulator of cell growth and underscore a link between the above-mentioned cyclins, cyclin-associated molecules and tumorigenicity. PMID: 16077900
5. Promotes neurite extension of hippocampal neurons, and induces differentiation of glioblastoma U251 cells into astrocyte-like cells. PMID: 17928921
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亞細胞定位：

Membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane.
組織特異性：

Specifically expressed in brain. In the hippocampus, parietal cortex and piriform cortex expressed in proximal segments of CA1 pyramidal neurons.
數據庫鏈接：

KEGG: mmu:192198

STRING: 10090.ENSMUSP00000062158

UniGene: Mm.443660