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  4. Recombinant Mouse Interleukin-17 receptor B (Il17rb), partial

Recombinant Mouse Interleukin-17 receptor B (Il17rb), partial

  • 中文名稱：
    小鼠Il17rb重組蛋白
  • 貨號：
    CSB-YP872844MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Il17rb重組蛋白
  • 貨號：
    CSB-EP872844MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Il17rb重組蛋白
  • 貨號：
    CSB-EP872844MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Il17rb重組蛋白
  • 貨號：
    CSB-BP872844MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Il17rb重組蛋白
  • 貨號：
    CSB-MP872844MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Il17rb; Evi27; Il17br; Interleukin-17 receptor B; IL-17 receptor B; IL-17RB; IL-17 receptor homolog 1; IL-17ER; IL-17Rh1; IL17Rh1; Interleukin-17B receptor; IL-17B receptor
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.
  • 基因功能參考文獻：
    1. IL-17E (IL-25) and IL-17RB promote respiratory syncytial virus-induced pulmonary disease PMID: 24407884
    2. Results show that amplified signaling of interleukin-17 receptor B (IL-17RB) and its ligand IL-17B promot tumorigenicity in breast cancer cells and impeded acinus formation in immortalized normal mammary epithelial cells. PMID: 23851503
    3. data establish IL-25 and its receptor IL-17RB as targets for innate and adaptive immune responses in chronic allergic airway disease and identify T2M cells as a new steroid-resistant cell population PMID: 22543263
    4. IL-25-mediated activities require both IL-17RB and IL-17RA in this example of an IL-17 family ligand that utilizes a heteromeric receptor complex. PMID: 18768888
    5. Results identify a novel subset of natural killer T cells that expresses the interleukin 17 receptor B (IL-17RB) for IL-25 and is essential for the induction of the airway hypersensitive reaction. PMID: 19015310
    6. IL-17RB(+) iNKT cells were detected in the lungs of wild-type mice, and induction of airway hyperreactivity by intranasal administration of IL-25 was significantly impaired in iNKT cell-deficient mice PMID: 19342692
    7. IL-17RB-positive cells in the bone marrow also express CD11B, GR1, and c-kit, potentially suggesting a maturation of the bone marrow cell once it enters the inflamed lung. PMID: 19828636

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  • 亞細胞定位：
    [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
  • 組織特異性：
    Liver and testis. Expressed at lower level in kidney and lung. Expressed in selected T-cell, B-cell and myeloid cell lines.
  • 數據庫鏈接：


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