Recombinant Mouse Early growth response protein 4 (Egr4)

中文名稱：

小鼠Egr4重組蛋白
貨號：

CSB-YP892987MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Egr4重組蛋白
貨號：

CSB-EP892987MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Egr4重組蛋白
貨號：

CSB-EP892987MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Egr4重組蛋白
貨號：

CSB-BP892987MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Egr4重組蛋白
貨號：

CSB-MP892987MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Egr4
Uniprot No.：

Q9WUF2
別名：

Egr4Early growth response protein 4; EGR-4
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區(qū)域：

1-478
氨基酸序列

MLHLSDFSGS DALLSKPTEG CAHASPELPR LPARDAPSAA AYPGGDFLSW ALSSCGAGGD LTDSCFLEGP APTPPSGLSY SGSFFIQAVP EHPHDPEALF NLMSGILGLA PFPGPEAAAS RSPLDVPFPA GPDALLPDLY SPDLSSAAFP EAFWEAAPSA GAPSQCLFEP QLSPPDVKPG LRAPPASPAL DAAASAFKGP YAPWELLSAG VPGNCGSQGS FQTTPEARFS AVGTKVEDLL SISCPAELPG PAARLYQAGA YDTFSLAPGD LGEGTEGLPA LLTPPGGEGG SGGEGGEFLA APPAQLSPLG LRGAATADFS KPLVADLPGG SGVAAPSSPA ASFPAAKARR KGRRGGKCSA RCFCPRPHVK AFACPVESCV RSFARSDELN RHLRIHTGHK PFQCRICLRN FSRSDHLTTH VRTHTGEKPF ACDVCGRRFA RSDEKKRHSK VHLKQKARAE ERLKGLGFYS LGLSFAAL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCGGGGGCG-3' (GSG). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.
基因功能參考文獻：
1. Egr4 expression is triggered by trophic factor neurturin to upregulate K-Cl cotransporter KCC2 in immature neurons. PMID: 21837281
2. Egr4 is an important component in the mechanism of BDNF-dependent KCC2 gene regulation via the ERK1/2 pathway in immature neurons. PMID: 21228173
3. Data suggest that Egr4 may regulate spermatogenesis at multiple steps, with roles in the dividing Sertoli cells, peritubular myoid cells, and the meiotic and elongating haploid germ cell populations. PMID: 20925118
4. An important role for Egr4 is indicated in the developmental upregulation of potassium-chloride cotransporter (KCC2) gene expression. PMID: 17192429
亞細胞定位：

Nucleus.
蛋白家族：

EGR C2H2-type zinc-finger protein family
數(shù)據(jù)庫鏈接：

KEGG: mmu:13656

STRING: 10090.ENSMUSP00000093433

UniGene: Mm.44137