Recombinant Mouse Coiled-coil domain-containing protein 164 (Ccdc164)

中文名稱：

小鼠Drc1重組蛋白
貨號：

CSB-YP666281MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Drc1重組蛋白
貨號：

CSB-EP666281MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Drc1重組蛋白
貨號：

CSB-EP666281MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Drc1重組蛋白
貨號：

CSB-BP666281MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Drc1重組蛋白
貨號：

CSB-MP666281MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Drc1
Uniprot No.：

Q3USS3
別名：

Drc1; Ccdc164; Gm1060Dynein regulatory complex protein 1; Coiled-coil domain-containing protein 164
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-753
氨基酸序列

MNPSGTIGVL EQNGEEHLAT PILGPSVHSD NPQERIQARR LRIAARQEAR RREALGEYLD GKKESEEEQS KSYKQKEESR LKLTKLLLCG TELVTNIQVA ADVREIHRRV EEEETKRQRL EKLENEVKTS QDKFDEITAK WEEGRRKRIP QELWEMLNSQ QVHCAELIED KNKLANELQQ ELKIKDDQYV KDLKKQSEDI TLILERMEEQ VKNVMKNFRQ ELIHIEKAFE SERQELLSSN KKKWERALQA HNAKELEYLT NRMKKVEDYE KQLNKQRVWD CEEYNTIKIK LEQDVQILEQ QLQQMKATYQ LNQEKLEYNF QVLKKRDEES TVIKSQQKRK LNRLHDVVNN LRTKYTKQIR QFQDDNQSLT SDYKRLVTQF KDLQKALRHF IIIDEEKFRE IWLMNEAEAK ELAQRAFDVD RIIHSQHLGL PWNMPDLWFL NNVGPISLQQ QKSVTQILEE LLLQTEDEAT EAAMSEDEDY MDLPNQISAK TTTKVLMLLC DESGFLIESK LLSLLHPLEK SECYLLRLDA IFSALAIEDE DDLYKLVNFF LRYRAHRLSS AQASSSIHSN VERTSLMSAL ERLSLMSQTD KGSMVSKSDQ EPTEQEDEQE GDNASLSSRE LEEQEDLSSP RFIHPNDVLK ILEAFVTGLK KPKDAQPVLK LKKETRDNSK DTEYWESLAA VIPFFKQNLW DALYKALEKY YLVLTERAKL LMENESLEQQ NAEMQSLLQQ YLQAKVNTEL QIPPTQGFRM PSK
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with CCDC65/DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.
基因功能參考文獻：
1. Gm1060 is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia. PMID: 17971504
亞細胞定位：

Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
蛋白家族：

DRC1 family
數據庫鏈接：

KEGG: mmu:381738

STRING: 10090.ENSMUSP00000098992

UniGene: Mm.389604