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  4. Recombinant Mouse Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (Ctdsp2)

Recombinant Mouse Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (Ctdsp2)

  • 中文名稱：
    Recombinant Mouse Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2(Ctdsp2)
  • 貨號：
    CSB-YP803953MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2(Ctdsp2)
  • 貨號：
    CSB-EP803953MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2(Ctdsp2)
  • 貨號：
    CSB-EP803953MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2(Ctdsp2)
  • 貨號：
    CSB-BP803953MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2(Ctdsp2)
  • 貨號：
    CSB-MP803953MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Ctdsp2
  • Uniprot No.：
  • 別名：
    Ctdsp2; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; EC 3.1.3.16; Small C-terminal domain phosphatase 2; Small CTD phosphatase 2; SCP2
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-270
  • 氨基酸序列
    MEHGSIITQA RREDALVLTK QGLVSKSSPK KPRGRSIFKA LLCCFHTQHV VQSSSSTELT HKEEANTIAK SDLLQCLQYQ FYQIPGTCLL PEVTEQDQGR ICVVIDLDET LVHSSFKPIN NADFIVPVEI EGTTHQVYVL KRPYVDEFLR RMGELFECVL FTASLAKYAD PVTDLLDRCG VFRARLFREA CVFHQGCYVK DLSRLGRDLR KTVILDNSPA SYIFHPENAV PVQSWFDDMA DTELLNLIPV FEELSGTDDV YTSLGQLRAP
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
  • 基因功能參考文獻：
    1. CTDSP2 induces p21(Cip1/Waf1) through increasing the activity of Ras. PMID: 25990325
  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Expression is restricted to non-neuronal tissues.
  • 數據庫鏈接：


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