1. In clinical Esophageal squamous cell carcinoma (ESCC)specimens, BMF expression was upregulated, and negatively correlated with that of miR-125b. In conclusion, miR-125b had an antitumor role in ESCC cells mediated by targeting BMF, which can be potentially useful for tumorigenesis in ESCC PMID: 29749531
2. demonstrate that this sudden and dramatic loss of primordial follicles is hormonally triggered and identify the pro-apoptotic BH3-only protein, BCL-2 modifying factor (BMF), as essential for this process, implicating the intrinsic apoptotic pathway as a key mechanism. PMID: 28771225
3. FOXO-dependent BMF expression is repressed in E-cadherin-negative and metastatic breast cancer cells and that expression of BMFis sufficient to inhibit tumour growth and dissemination in mice. PMID: 27035620
4. BMF loss is associated with germ cell loss during oogenesis. PMID: 26917450
5. Bcl2 interacting mediator of cell death (Bim) and Bcl2 modifying factor (Bmf), mediate apoptosis in the context of TACI-Ig overexpression that effectively neutralizes BAFF as well as APRIL. PMID: 25698446
6. Bmf deficiency induced significant protection against oxygen/glucose deprivation injury in cultured neurons. PMID: 25299781
7. Our findings support an important role for BMF in determining the number of primordial follicles maintained in the ovary throughout adult reproductive life. PMID: 24571986
8. Bim and Bmf act in concert to prevent autoimmunity and malignant disease PMID: 24632712
9. Bmf-deficient mice showed normal sensitivity to the convulsant effects of KA, displayed significantly more neuronal death in the hippocampal CA1 and CA3 subfields after SE. PMID: 23618904
10. deacetylation of p53 suppresses Bmf expression and facilitates autophagy. PMID: 23629966
11. critical role for Bim and Bmf as regulators of hematopoietic stem and progenitor cell dynamics both during early engraftment and long-term reconstitution PMID: 23180554
12. our study suggests that Bad and Bmf co-regulate lymphocyte homeostasis and limit spontaneous transformation by mechanisms that may not exclusively be linked to the induction of lymphocyte apoptosis. PMID: 22430207
13. a potential role for Bmf in regulating renal proximal tubular cells (RPTC) apoptosis and tubular atrophy in diabetes. PMID: 22210314
14. characterization of the bmf gene locus; molecular basis of the generation of the 2 major isoforms of Bmf; provide evidence that Bmf can act as a sensor for stress that associates with the repression of the conventional CAP-dependent translation machinery PMID: 20706276
15. Data show that loss of Bmf reduced the pressure to inactivate p53, whereas Bad deficiency did not, identifying Bmf as a novel component of the p53-independent tumor suppressor pathway triggered by c-Myc. PMID: 19965635
16. Developmental ablation of interdigital webbing on mouse paws and normal lymphocyte homeostasis require the cooperative activity of Bim and Bmf. PMID: 19841067
17. Study shows, using spectroscopic methods, that the BH3-only proteins Bim, Bad and Bmf are unstructured in the absence of binding partners. PMID: 16645638
18. TGF beta-induced Bmf and Bim undergo significant expression changes, the combined effect of which is to trigger the cell death program. PMID: 16909112
19. Bmf is a central mediator of anoikis in mammary cells and a target of oncogenes that contribute to the progression of glandular epithelial tumors PMID: 17360431
20. Bmf plays a critical role in apoptosis signaling and can function as a tumor suppressor. PMID: 18299399

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KEGG: mmu:171543

STRING: 10090.ENSMUSP00000087686

UniGene: Mm.210125