Recombinant Mouse ATPase family AAA domain-containing protein 5 (Atad5), partial

中文名稱：

Recombinant Mouse ATPase family AAA domain-containing protein 5(Atad5) ,partial
貨號：

CSB-YP683933MO
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse ATPase family AAA domain-containing protein 5(Atad5) ,partial
貨號：

CSB-EP683933MO
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse ATPase family AAA domain-containing protein 5(Atad5) ,partial
貨號：

CSB-EP683933MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse ATPase family AAA domain-containing protein 5(Atad5) ,partial
貨號：

CSB-BP683933MO
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse ATPase family AAA domain-containing protein 5(Atad5) ,partial
貨號：

CSB-MP683933MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Atad5
Uniprot No.：

Q4QY64
別名：

Atad5; Frag1ATPase family AAA domain-containing protein 5; Chromosome fragility-associated gene 1 protein
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis.
基因功能參考文獻：
1. Atad5+/m cells accumulate in the S phase, have decreased proliferation, and have reduced double-strand breaks, class switch recombination, and translocations PMID: 25404367
2. Authors discuss many functions of Elg1 protein as embryonic lethal when lost in mice, as a tumor suppressor in mice and humans, interacts with human Fanconi Anemia pathway and may contribute to some of the phenotypes associated with neurofibromatosis. [Review] PMID: 25795125
3. loss-of-function mutations in mammalian Atad5 are sufficient to cause genomic instability and tumorigenesis. PMID: 21901109
亞細胞定位：

Nucleus.
蛋白家族：

AAA ATPase family
組織特異性：

Expressed ubiquitously in all cell lines like teratocarcinoma, cell lymphoma, lymphoma.
數據庫鏈接：

KEGG: mmu:237877

STRING: 10090.ENSMUSP00000017694

UniGene: Mm.89551