Recombinant Lysine-specific demethylase rbr-2 (rbr-2), partial

中文名稱：

秀麗隱桿線蟲rbr-2重組蛋白
貨號：

CSB-YP631522CXY
規格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲rbr-2重組蛋白
貨號：

CSB-EP631522CXY
規格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲rbr-2重組蛋白
貨號：

CSB-EP631522CXY-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲rbr-2重組蛋白
貨號：

CSB-BP631522CXY
規格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲rbr-2重組蛋白
貨號：

CSB-MP631522CXY
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

rbr-2
Uniprot No.：

Q23541
別名：

rbr-2; ZK593.4Lysine-specific demethylase rbr-2; Histone demethylase rbr-2; EC 1.14.11.-; Jumonji/ARID domain-containing protein rbr-2
種屬：

Caenorhabditis elegans
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Required for normal longevity of the soma in a germline-dependent manner. Implicated in the epigenetic inheritance of lifespan over several generations. Involved in larval development and vulva formation.
基因功能參考文獻：
1. RBR-2 is not involved in preventing H3K4me3 deposition in the P lineage, but could play a role in regulating somatic deposition of H3K4me3. PMID: 21549110
2. findings show that mutation or RNAi depletion of rbr-2 leads to increased levels of trimethylated histone 3 lysine 4 during larval development and defects in vulva formation PMID: 17320161
亞細胞定位：

Nucleus.
蛋白家族：

JARID1 histone demethylase family
數據庫鏈接：

KEGG: cel:CELE_ZK593.4

STRING: 6239.ZK593.4

UniGene: Cel.6207