Recombinant Loxosceles gaucho Sphingomyelin phosphodiesterase D LgSicTox-alphaIA1

中文名稱：

Recombinant Loxosceles gaucho Sphingomyelin phosphodiesterase D LgSicTox-alphaIA1
貨號：

CSB-YP706320LJE
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Loxosceles gaucho Sphingomyelin phosphodiesterase D LgSicTox-alphaIA1
貨號：

CSB-EP706320LJE
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Loxosceles gaucho Sphingomyelin phosphodiesterase D LgSicTox-alphaIA1
貨號：

CSB-EP706320LJE-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Loxosceles gaucho Sphingomyelin phosphodiesterase D LgSicTox-alphaIA1
貨號：

CSB-BP706320LJE
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Loxosceles gaucho Sphingomyelin phosphodiesterase D LgSicTox-alphaIA1
貨號：

CSB-MP706320LJE
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

N/A
Uniprot No.：

Q4VDB5
別名：

Dermonecrotic toxin LgSicTox-alphaIA1; EC 4.6.1.-; Phospholipase D; PLD; Sphingomyelin phosphodiesterase D 1; SMD 1; SMase D 1; Sphingomyelinase D 1
種屬：

Loxosceles gaucho (Spider)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-280
氨基酸序列

AGNRRPIWIM GHMVNAIGQI DEFVNLGANS IETDVSFDDN ANPEYTYHGI PCDSGRNCKK YENFNDFLKG LRSATTPGNS KYQEKLVLVV FDLKTGSLYD NQANDAGKKW AKNLLQHYWN NGNNGGRAYI VLSIPDLNHY PLIKGFKDQL TKDGHPELMD KVGHDFSGND DISDVGKAYK KAGITGHIWQ SDGITNSLPR GLSRVNAAVA NRDSANGFIN KVYYWTVDKR STTRDALDAG VDGIMTNYPD VITDVLNEAA YKKKFRVATY DDNPWVTFNK
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate. This toxin acts on sphingomyelin (SM). It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG). It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products. Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation.
亞細(xì)胞定位：

Secreted.
蛋白家族：

Arthropod phospholipase D family, Class I subfamily
組織特異性：

Expressed by the venom gland.