Recombinant Human Zinc finger and SCAN domain-containing protein 10 (ZSCAN10)

中文名稱：

人ZSCAN10重組蛋白
貨號(hào)：

CSB-YP857029HU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人ZSCAN10重組蛋白
貨號(hào)：

CSB-EP857029HU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人ZSCAN10重組蛋白
貨號(hào)：

CSB-EP857029HU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人ZSCAN10重組蛋白
貨號(hào)：

CSB-BP857029HU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人ZSCAN10重組蛋白
貨號(hào)：

CSB-MP857029HU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

ZSCAN10
Uniprot No.：

Q96SZ4
別名：

ZSCAN10; ZNF206; Zinc finger and SCAN domain-containing protein 10; Zinc finger protein 206
種屬：

Homo sapiens (Human)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-725
氨基酸序列

MGPRASLSRL RELCGHWLRP ALHTKKQILE LLVLEQFLSV LPPHLLGRLQ GQPLRDGEEV VLLLEGIHRE PSHAGPLDFS CNAGKSCPRA DVTLEEKGCA SQVPSHSPKK ELPAEEPSVL GPSDEPPRPQ PRAAQPAEPG QWRLPPSSKQ PLSPGPQKTF QALQESSPQG PSPWPEESSR DQELAAVLEC LTFEDVPENK AWPAHPLGFG SRTPDKEEFK QEEPKGAAWP TPILAESQAD SPGVPGEPCA QSLGRGAAAS GPGEDGSLLG SSEILEVKVA EGVPEPNPEL QFICADCGVS FPQLSRLKAH QLRSHPAGRS FLCLCCGKSF GRSSILKLHM RTHTDERPHA CHLCGHRFRQ SSHLSKHLLT HSSEPAFLCA ECGRGFQRRA SLVQHLLAHA QDQKPPCAPE SKAEAPPLTD VLCSHCGQSF QRRSSLKRHL RIHARDKDRR SSEGSGSRRR DSDRRPFVCS DCGKAFRRSE HLVAHRRVHT GERPFSCQAC GRSFTQSSQL VSHQRVHTGE KPYACPQCGK RFVRRASLAR HLLTHGGPRP HHCTQCGKSF GQTQDLARHQ RSHTGEKPCR CSECGEGFSQ SAHLARHQRI HTGEKPHACD TCGHRFRNSS NLARHRRSHT GERPYSCQTC GRSFRRNAHL RRHLATHAEP GQEQAEPPQE CVECGKSFSR SCNLLRHLLV HTGARPYSCT QCGRSFSRNS HLLRHLRTHA RETLY
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Embryonic stem (ES) cell-specific transcription factor required to maintain ES cell pluripotency. Can both activate and /or repress expression of target genes, depending on the context. Specifically binds the 5'-[GA]CGCNNGCG[CT]-3' DNA consensus sequence. Regulates expression of POU5F1/OCT4, ZSCAN4 and ALYREF/THOC4.
基因功能參考文獻(xiàn)：
1. The pluripotency factor ZSCAN10 is poorly expressed in A-iPSCs and addition of ZSCAN10 to the four Yamanaka factors (OCT4, SOX2, KLF4 and c-MYC) during A-iPSC reprogramming normalizes ROS-glutathione homeostasis and the DNA damage response, and recovers genomic stability. PMID: 28846095
2. We demonstrated that SLC16A5 and ZNF206 displayed altered methylation patterns in the neuroblastoma genome PMID: 22911660
3. Data indicates that changes in DNA methylation levels at the Zfp206-exon 5 might be one of the important factors during neuronal development in mice and the hypomethylation of the homologous region induced ZNF206 expression in humans. PMID: 22011711
亞細(xì)胞定位：

Nucleus.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 12997

KEGG: hsa:84891

STRING: 9606.ENSP00000252463

UniGene: Hs.334515