Recombinant Human Ventricular zone-expressed PH domain-containing protein homolog 1 (VEPH1), partial

中文名稱：

人VEPH1重組蛋白
貨號：

CSB-YP617949HU
規格：
來源：

Yeast
其他：

中文名稱：

人VEPH1重組蛋白
貨號：

CSB-EP617949HU
規格：
來源：

E.coli
其他：

中文名稱：

人VEPH1重組蛋白
貨號：

CSB-EP617949HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人VEPH1重組蛋白
貨號：

CSB-BP617949HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人VEPH1重組蛋白
貨號：

CSB-MP617949HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

VEPH1
Uniprot No.：

Q14D04
別名：

2810471M23Rik; MELT; MELT_HUMAN; Protein melted; RGD1308217; Ventricular zone-expressed PH domain-containing protein homolog 1; VEPH; Veph1
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Interacts with TGF-beta receptor type-1 (TGFBR1) and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumulation and resulting in impaired TGF-beta signaling. May also affect FOXO, Hippo and Wnt signaling.
基因功能參考文獻：
1. Low VEPH1 expression is associated with ovarian cancer. PMID: 28301874
2. studies indicate that VEPH1 inhibits TGF-beta signaling by impeding the release of activated SMAD2 from TbetaRI and may modulate TGF-beta signaling during development and cancer initiation or progression PMID: 26039994
亞細胞定位：

Cell membrane; Peripheral membrane protein; Cytoplasmic side.
蛋白家族：

MELT/VEPH family
數據庫鏈接：

HGNC: 25735

OMIM: 609594

KEGG: hsa:79674

STRING: 9606.ENSP00000354919

UniGene: Hs.658046