Recombinant Human Hematological and neurological expressed 1-like protein (HN1L)

中文名稱：

人JPT2重組蛋白
貨號：

CSB-YP867176HU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人JPT2重組蛋白
貨號：

CSB-EP867176HU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人JPT2重組蛋白
貨號：

CSB-EP867176HU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人JPT2重組蛋白
貨號：

CSB-BP867176HU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人JPT2重組蛋白
貨號：

CSB-MP867176HU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

JPT2
Uniprot No.：

Q9H910
別名：

C16orf34; Chromosome 16 open reading frame 34; CRAMP1 like; FLJ13092; Hematological and neurological expressed 1 like; Hematological and neurological expressed 1 like protein; Hematological and neurological expressed 1-like protein; HN1 like; HN1 like protein; HN1-like protein; Hn1l; HN1L_HUMAN; L11
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區(qū)域：

1-190
氨基酸序列

MFQVPDSEGG RAGSRAMKPP GGESSNLFGS PEEATPSSRP NRMASNIFGP TEEPQNIPKR TNPPGGKGSG IFDESTPVQT RQHLNPPGGK TSDIFGSPVT ATSRLAHPNK PKDHVFLCEG EEPKSDLKAA RSIPAGAEPG EKGSARKAGP AKEQEPMPTV DSHEPRLGPR PRSHNKVLNP PGGKSSISFY
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

基因功能參考文獻：
1. reveal that breast cancer stem cell (BCSC) in triple-negative breast cancer depend on the transcription regulator HN1L for the sustained activation of the LEPR-STAT3 pathway, which makes it a potentially important target for both prognosis and BCSC therapy. PMID: 29249663
2. The positive correlation of HN1L expression and Ki67 level in a large NSCLC samples further suggested the key role of HN1L in the regulation of cell growth. Further study showed that knockdown of HN1L resulted in dramatic cell cycle arrest by interfering with MAPK pathway via interacting with RASA4 protein. PMID: 29053395
亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

JUPITER family
組織特異性：

Expressed in liver, kidney, prostate, testis and uterus.
數(shù)據(jù)庫鏈接：

HGNC: 14137

KEGG: hsa:90861

STRING: 9606.ENSP00000248098

UniGene: Hs.513261