Recombinant Drosophila melanogaster Serine/threonine-protein phosphatase 4 regulatory subunit 3 (flfl), partial

中文名稱：

黑腹果蠅flfl重組蛋白
貨號(hào)：

CSB-YP893273DLU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

黑腹果蠅flfl重組蛋白
貨號(hào)：

CSB-EP893273DLU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

黑腹果蠅flfl重組蛋白
貨號(hào)：

CSB-EP893273DLU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅flfl重組蛋白
貨號(hào)：

CSB-BP893273DLU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

黑腹果蠅flfl重組蛋白
貨號(hào)：

CSB-MP893273DLU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

flfl
Uniprot No.：

Q9VFS5
別名：

flfl; CG9351; Serine/threonine-protein phosphatase 4 regulatory subunit 3; PP4R3; Protein falafel
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Regulatory subunit of serine/threonine-protein phosphatase 4. The probable PP4 complex Pp4-19C-PPP4R2r-flfl (PPP4C-PPP4R2-PPP4R3) is required to prevent caspase induced cell death (in vitro). May be involved in DNA damage repair. Key mediator specific for the localization of mira and associated cell fate determinants during both interphase and mitosis. Nuclear Flfl is required to exclude mira/pros from the nucleus when inefficiently bound to the cytoskeleton/cortex, whereas cytosolic or membrane-associated flfl is required for the cortical association and asymmetric localization of mira/pros/brat/stau at metaphase and anaphase.
基因功能參考文獻(xiàn)：
1. These data report for the first time an essential physiological function of flfl in maintaining tissue homeostasis and organ development PMID: 26583122
2. identified the evolutionarily conserved Protein Phosphatase 4 (PP4) regulatory subunit PP4R3/Falafel (Flfl) as a key mediator specific for the localization of Miranda (Mira) and associated cell fate determinants during both interphase and mitosis PMID: 19204120
亞細(xì)胞定位：

Nucleus. Membrane. Cytoplasm. Note=Predominantly nuclear during interphase/prophase and cytoplasmic after nuclear envelope breakdown.
蛋白家族：

SMEK family
組織特異性：

Expressed in neuroblasts.
數(shù)據(jù)庫(kù)鏈接：

KEGG: dme:Dmel_CG9351

STRING: 7227.FBpp0082285

UniGene: Dm.14510