Recombinant Drosophila melanogaster SOX domain-containing protein dichaete (D)

中文名稱：

Recombinant Drosophila melanogaster SOX domain-containing protein dichaete(D)
貨號：

CSB-YP635527DLU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Drosophila melanogaster SOX domain-containing protein dichaete(D)
貨號：

CSB-EP635527DLU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Drosophila melanogaster SOX domain-containing protein dichaete(D)
貨號：

CSB-EP635527DLU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Drosophila melanogaster SOX domain-containing protein dichaete(D)
貨號：

CSB-BP635527DLU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Drosophila melanogaster SOX domain-containing protein dichaete(D)
貨號：

CSB-MP635527DLU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

D
Uniprot No.：

Q24533
別名：

D; fish; Sox70D; CG5893SOX domain-containing protein dichaete; Protein fish-hook
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

full length protein
表達區(qū)域：

1-382
氨基酸序列

MATLSTHPNY GFHLGQAQGL EDYAPQSQLQ LSPGMDMDIK RVLHYSQSLA AMGGSPNGPA GQGVNGSSGM GHHMSSHMTP HHMHQAVSAQ QTLSPNSSIG SAGSLGSQSS LGSNGSGLNS SSGHQSAGMH SLATSPGQEG HIKRPMNAFM VWSRLQRRQI AKDNPKMHNS EISKRLGAEW KLLAESEKRP FIDEAKRLRA LHMKEHPDYK YRPRRKPKNP LTAGPQGGLQ MQAGGMGQQK LGAGPGAGAG GYNPFHQLPP YFAPSHHLDQ GYPVPYFGGF DPLALSKLHQ SQAAAAAAVN NQGQQQGQAP PQLPPTSLSS FYSGIYSGIS APSLYAAHSA NAAGLYPSSS TSSPGSSPGT ITPNGMDGSM DSALRRPVPV LY
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Essential for segmentation and CNS development. May modulate the actions of other transcription factors, including gap and pair-rule proteins.
基因功能參考文獻：
1. Analysis of the functional relationship between SoxNeuro and Dichaete uncovers evidence for redundant and independent functions for each protein, along with unexpected examples of compensation and interdependency. PMID: 24886562
2. Dichaete acts as a transcriptional hub, controlling multiple regulatory pathways during CNS development. PMID: 24314314
3. the early neurectoderm we implicate Dichaete in the lateral inhibition pathway and show that Dichaete acts to repress the proneural gene asense PMID: 23289785
4. These results suggest noncell autonomous functions of Dichaete in projection neuron differentiation as well as a potential role for Dichaete-expressing local interneurons PMID: 22648855
5. Data show that Dichaete appears to be a novel phosphorylation substrate for Pelle and may function in a Pelle-dependent signaling pathway during oogenesis. PMID: 20563992
6. Evidence for differential and redundant function of the Sox genes during CNS development in Drosophila PMID: 12183374
7. Results show that expression of Dichaete protein is detected in the developing oocyte during early to mid stages of oogenesis, exhibits cytoplasmic distribution, and plays a direct post-transcriptional role in regulating RNA functions. PMID: 16894603
8. The expression of svb in a discreet domain is resolved at the level of SoxN and Dichaete. PMID: 17611224
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亞細胞定位：

Nucleus.
組織特異性：

Initially expressed in a pair-rule-like pattern which is rapidly replaced by strong neuroectoderm expression.
數(shù)據(jù)庫鏈接：

KEGG: dme:Dmel_CG5893

STRING: 7227.FBpp0075488

UniGene: Dm.1835