Recombinant Drosophila melanogaster SAGA-associated factor 11 homolog (Sgf11)

中文名稱：

黑腹果蠅Sgf11重組蛋白
貨號：

CSB-YP893337DLU
規格：
來源：

Yeast
其他：

中文名稱：

黑腹果蠅Sgf11重組蛋白
貨號：

CSB-EP893337DLU
規格：
來源：

E.coli
其他：

中文名稱：

黑腹果蠅Sgf11重組蛋白
貨號：

CSB-EP893337DLU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅Sgf11重組蛋白
貨號：

CSB-BP893337DLU
規格：
來源：

Baculovirus
其他：

中文名稱：

黑腹果蠅Sgf11重組蛋白
貨號：

CSB-MP893337DLU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Sgf11
Uniprot No.：

Q9VVR6
別名：

Sgf11; CG13379; SAGA-associated factor 11 homolog
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

full length protein
表達區域：

1-196
氨基酸序列

MSAANMPTTT GAQGSGNQVP TTSTTIVNHF RELIKEPKNL DEAANYLYQS LLDDAVVGIF NETHHLRKSG NLAALDGVPE DSTYRMCEMP NLDIFGISTA KKPMDCTCPN CDRLVAAARF APHLEKCMGM GRISSRIASR RLATKEGATS AHLHSSGNTG GTDDEDDVDW SSDKRRKKSN QNSRNNGSKK NNGKTF
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Binds independently on SAGA to promoters in an RNA-dependent manner. Binds to mRNA and is essential for total mRNA export from the nucleus. Required to counteract heterochromatin silencing. Controls the development of neuronal connectivity in visual system by being required for accurate axon targeting in the optic lobe. Required for expression of ecdysone-induced genes such as br/broad.
基因功能參考文獻：
1. Study described the formation of mutually exclusive complexes of ENY2 with insulator proteins and Sgfl1-a component of the SAGA complex, direct binding partner for ENY2 PMID: 27417714
2. The results show that Drosophila Sgf11, a component of the deubiquitination module of SAGA, has a function in general mRNA export. PMID: 22989713
亞細胞定位：

Nucleus, nucleoplasm. Cytoplasm. Note=Localizes to nuclear periphery, in contact with the nuclear pore complex (NPC).
蛋白家族：

SGF11 family
數據庫鏈接：

KEGG: dme:Dmel_CG13379

STRING: 7227.FBpp0112092

UniGene: Dm.15168