Recombinant Drosophila melanogaster Protein wings apart-like (wapl), partial

中文名稱：

黑腹果蠅wapl重組蛋白
貨號(hào)：

CSB-YP894314DLU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

黑腹果蠅wapl重組蛋白
貨號(hào)：

CSB-EP894314DLU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

黑腹果蠅wapl重組蛋白
貨號(hào)：

CSB-EP894314DLU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅wapl重組蛋白
貨號(hào)：

CSB-BP894314DLU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

黑腹果蠅wapl重組蛋白
貨號(hào)：

CSB-MP894314DLU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

wapl
Uniprot No.：

Q9W517
別名：

wapl; pasc; CG3707Protein wings apart-like; Protein parallel sister chromatids
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Has a role in female meiotic chromosome segregation in females; proximal heterochromatin is involved in chromosome pairing during female meiosis. Is a dominant suppressor of both white and Stubble position-effect variegation (PEV), while it is a weak enhancer of brown variegation.
基因功能參考文獻(xiàn)：
1. findings suggests that the mutant Wapl-AG might exert its effects through changes in cohesin binding; Wapl-AG was found to increase the stability of cohesin binding to polytene chromosomes PMID: 23034634
2. Study shows that DNA replication and cohesin acetylation promote binding of Sororin to cohesin, and that Sororin displaces Wapl from its binding partner Pds5; in the absence of Wapl, Sororin becomes dispensable for cohesion. PMID: 21111234
3. Nipped-B, Pds5, and the Wapl protein that interacts with Pds5 all play unique roles in cohesin chromosome binding. PMID: 20696838
蛋白家族：

WAPL family
數(shù)據(jù)庫(kù)鏈接：

KEGG: dme:Dmel_CG3707

STRING: 7227.FBpp0070413