Recombinant Drosophila melanogaster Protein lethal (2)denticleless (l (2)dtl), partial
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中文名稱：黑腹果蠅l(2)dtl重組蛋白
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貨號：CSB-YP630510DLU
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規格：
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來源：Yeast
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其他：
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中文名稱：黑腹果蠅l(2)dtl重組蛋白
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貨號：CSB-EP630510DLU
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規格：
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來源：E.coli
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其他：
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中文名稱：黑腹果蠅l(2)dtl重組蛋白
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貨號：CSB-EP630510DLU-B
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規格：
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來源：E.coli
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共軛：Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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其他：
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中文名稱：黑腹果蠅l(2)dtl重組蛋白
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貨號：CSB-BP630510DLU
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規格：
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來源：Baculovirus
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其他：
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中文名稱：黑腹果蠅l(2)dtl重組蛋白
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貨號：CSB-MP630510DLU
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規格：
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來源：Mammalian cell
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其他：
產品詳情
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純度：>85% (SDS-PAGE)
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基因名：l(2)dtl
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Uniprot No.：
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別名：l(2)dtl; DTL83; CG11295; Protein lethal(2)denticleless; Protein DTL83
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種屬：Drosophila melanogaster (Fruit fly)
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蛋白長度：Partial
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蛋白標簽：Tag?type?will?be?determined?during?the?manufacturing?process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially. -
產品提供形式：Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
復溶：We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
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儲存條件：Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保質期：The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期：Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
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注意事項：Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet ：Please contact us to get it.
產品評價
靶點詳情
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功能：Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of E2f during S phase. E2f degradation is necessary to ensure proper development. Substrates require their interaction with PCNA for their polyubiquitination: substrates interact with PCNA via their PIP-box, leading to recruit the DCX(DTL) complex.
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基因功能參考文獻：
- L(2)dtl is essential for Drosophila development. PMID: 22722696
- L2DTL and PCNA interact with CUL4/DDB1 complexes and are involved in CDT1 degradation after DNA damage. PMID: 16861906
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亞細胞定位：Cytoplasm.
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蛋白家族：WD repeat cdt2 family
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組織特異性：Ubiquitously expressed during embryogenesis with no sign of tissue specificity in expression up to stage 17.
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數據庫鏈接：
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