Recombinant Drosophila melanogaster Protein deltex (dx), partial

中文名稱：

黑腹果蠅dx重組蛋白
貨號：

CSB-YP631531DLU
規格：
來源：

Yeast
其他：

中文名稱：

黑腹果蠅dx重組蛋白
貨號：

CSB-EP631531DLU
規格：
來源：

E.coli
其他：

中文名稱：

黑腹果蠅dx重組蛋白
貨號：

CSB-EP631531DLU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅dx重組蛋白
貨號：

CSB-BP631531DLU
規格：
來源：

Baculovirus
其他：

中文名稱：

黑腹果蠅dx重組蛋白
貨號：

CSB-MP631531DLU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

dx
Uniprot No.：

Q23985
別名：

dx; CG3929Protein deltex; Probable E3 ubiquitin-protein ligase deltex; EC 2.3.2.27; RING-type E3 ubiquitin transferase deltex
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it may also act as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch. May function as a ubiquitin ligase protein in the Notch pathway.
基因功能參考文獻：
1. we observed that Dx together with Hrp48 can regulate Notch signaling in an Sxl-independent manner. In addition, Dx and Hrp48 displayed a synergistic effect on caspase-mediated cell death. Our results suggest that Dx and Hrp48 together negatively regulate Notch signaling in Drosophila melanogaster. PMID: 28396507
2. oligomerization mediated by the RING-H2 finger motif is an integral step in the signaling function of Deltex.(regulation of Notch signaling) PMID: 11861487
3. the accumulation of Notch (N) in the late-endosome was required for the Dx-mediated Su(H)-independent N signaling PMID: 15496440
亞細胞定位：

Cytoplasm.
蛋白家族：

Deltex family
組織特異性：

Ubiquitous. Expressed at low levels throughout embryogenesis and in larvae.
數據庫鏈接：

KEGG: dme:Dmel_CG3929

STRING: 7227.FBpp0070876

UniGene: Dm.2626