Recombinant Drosophila melanogaster Pre-mRNA-splicing regulator female-lethal (2)D (fl (2)d), partial

中文名稱：

黑腹果蠅fl(2)d重組蛋白
貨號：

CSB-YP896679DLU
規格：
來源：

Yeast
其他：

中文名稱：

黑腹果蠅fl(2)d重組蛋白
貨號：

CSB-EP896679DLU
規格：
來源：

E.coli
其他：

中文名稱：

黑腹果蠅fl(2)d重組蛋白
貨號：

CSB-EP896679DLU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅fl(2)d重組蛋白
貨號：

CSB-BP896679DLU
規格：
來源：

Baculovirus
其他：

中文名稱：

黑腹果蠅fl(2)d重組蛋白
貨號：

CSB-MP896679DLU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

fl(2)d
Uniprot No.：

Q9Y091
別名：

fl(2)d; CG6315Pre-mRNA-splicing regulator female-lethal(2)D; dFL(2)D
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. Required for proper inclusion of regulated exons in Ubx transcripts, leading to isoforms Ia/b and IIa/b.
基因功能參考文獻：
1. The Drosophila Wilms Tumor 1-Associating Protein (WTAP) homolog (Fl(2)d) is required for eye development. PMID: 24690230
2. biochemical function of of this protein in alternative pre-mRNA splicing PMID: 12444081
3. fl(2)d was localized in somatic cells and the ovary. PMID: 15778853
4. Sxl and fl(2)d genes function to alter splice-site selection at an early step in spliceosome assembly. PMID: 18245840
亞細胞定位：

Nucleus.
蛋白家族：

Fl(2)d family
數據庫鏈接：

KEGG: dme:Dmel_CG6315

STRING: 7227.FBpp0086773

UniGene: Dm.1511