Recombinant Drosophila melanogaster Eukaryotic translation initiation factor 2-alpha kinase (PEK), partial

中文名稱：

黑腹果蠅PEK重組蛋白
貨號(hào)：

CSB-YP889055DLU
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

黑腹果蠅PEK重組蛋白
貨號(hào)：

CSB-EP889055DLU
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

黑腹果蠅PEK重組蛋白
貨號(hào)：

CSB-EP889055DLU-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅PEK重組蛋白
貨號(hào)：

CSB-BP889055DLU
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

黑腹果蠅PEK重組蛋白
貨號(hào)：

CSB-MP889055DLU
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

PEK
Uniprot No.：

Q9NIV1
別名：

PEK; EIF2AK3; CG2087Eukaryotic translation initiation factor 2-alpha kinase; EC 2.7.11.1; PRKR-like endoplasmic reticulum kinase; DmPEK; PEK; PERK
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis.
基因功能參考文獻(xiàn)：
1. PERK and GCN2 act on FOXO to potentiate FOXO activity which has been implicated in the development and progression of a variety of diseases. PMID: 30043468
2. We show that the PKR-like ER kinase (PERK) integrates both cell-autonomous and non-autonomous endoplasmic reticulum stress stimuli to induce intestinal stem cell proliferation. PMID: 25945494
亞細(xì)胞定位：

Endoplasmic reticulum membrane; Single-pass type I membrane protein.
蛋白家族：

Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily
數(shù)據(jù)庫(kù)鏈接：

KEGG: dme:Dmel_CG2087

STRING: 7227.FBpp0078417

UniGene: Dm.3303