Recombinant Double-strand break repair protein mre-11 (mre-11), partial

中文名稱：

秀麗隱桿線蟲mre-11重組蛋白
貨號：

CSB-YP637565CXY
規格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲mre-11重組蛋白
貨號：

CSB-EP637565CXY
規格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲mre-11重組蛋白
貨號：

CSB-EP637565CXY-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲mre-11重組蛋白
貨號：

CSB-BP637565CXY
規格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲mre-11重組蛋白
貨號：

CSB-MP637565CXY
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

mre-11
Uniprot No.：

Q23255
別名：

mre-11; ZC302.1; Double-strand break repair protein mre-11
種屬：

Caenorhabditis elegans
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. In response to ionizing radiation, probably required for the association between the brc-1-brd-1 heterodimer and rad-51 and let-70 in order to activate E3-ubiquitin ligase activity of the heterodimer and induce ubiquitination at DNA damage sites.; Required for meiotic crossing over and chiasma formation. Pachytene morphology and homolog pairing are normal. Vital in long term for maintenance of reproductive capacity of subsequent generations.
基因功能參考文獻：
1. A novel role for MRE-11 in the resection of double strand breaks in middle meiotic prophase I and in blocking nonhomologous end joining. PMID: 23671188
亞細胞定位：

Nucleus.
蛋白家族：

MRE11/RAD32 family
數據庫鏈接：

KEGG: cel:CELE_ZC302.1

STRING: 6239.ZC302.1.2

UniGene: Cel.2948