Recombinant DNA- (apurinic or apyrimidinic site) lyase (apn-1)

中文名稱：

Recombinant DNA-(apurinic or apyrimidinic site) lyase(apn-1)
貨號：

CSB-YP611897CXY
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant DNA-(apurinic or apyrimidinic site) lyase(apn-1)
貨號：

CSB-EP611897CXY
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant DNA-(apurinic or apyrimidinic site) lyase(apn-1)
貨號：

CSB-EP611897CXY-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant DNA-(apurinic or apyrimidinic site) lyase(apn-1)
貨號：

CSB-BP611897CXY
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant DNA-(apurinic or apyrimidinic site) lyase(apn-1)
貨號：

CSB-MP611897CXY
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

apn-1
Uniprot No.：

Q10002
別名：

apn-1; T05H10.2DNA-(apurinic or apyrimidinic site) lyase; EC 4.2.99.18; Apurinic-apyrimidinic endonuclease; AP endonuclease
種屬：

Caenorhabditis elegans
蛋白長度：

full length protein
表達區(qū)域：

1-396
氨基酸序列

MANKKVTFRE DVKSPAIRKL KQKLTPLKIK KGRGKIQKHI QKTLQKMKEE EESENQSPGT TVEETLTEEN ISTDKEETSK LENKPKKTRK TSGETIAQKK SRETVGVEVL KTSEGSSKML GFHVSAAGGL EQAIYNARAE GCRSFAMFVR NQRTWNHKPM SEEVVENWWK AVRETNFPLD QIVPHGSYLM NAGSPEAEKL EKSRLAMLDE CQRAEKLGIT MYNFHPGSTV GKCEKEECMT TIAETIDFVV EKTENIILVL ETMAGQGNSI GGTFEELKFI IDKVKVKSRV GVCIDTCHIF AGGYDIRTQK AYEEVMKNFG EVVGWNYLKA IHINDSKGDV GSKLDRHEHI GQGKIGKAAF ELLMNDNRLD GIPMILETPE GKYPEEMMIM YNMDKR
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

基因功能參考文獻：
1. Purified APN-1 displays AP endonuclease activity, 3'-diesterase activity, 3'- to 5'-exonuclease activity and the nucleotide incision repair activity. PMID: 22819077
2. results show that apurinic/apyrimidinic endonuclease 1/EXO-3, p53/CEP-1, and thioredoxin affect each other and that these interactions determine aging as well as neuronal structure and function PMID: 20346071
3. APN-1 is an important apurinic/apyrimidinc endonuclease for repair of misincorporated uracil. PMID: 20036200
4. Apn-1 expresses apurinic/apyrimidinic endonuclease in a Saccharomyces cerevisiae mutant. PMID: 15907773
亞細胞定位：

Nucleus.
蛋白家族：

AP endonuclease 2 family
數(shù)據(jù)庫鏈接：

KEGG: cel:CELE_T05H10.2

STRING: 6239.T05H10.2.1

UniGene: Cel.32771