Recombinant Bovine Serine/threonine-protein kinase VRK1 (VRK1)

中文名稱：

牛VRK1重組蛋白
貨號：

CSB-YP655594BO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

牛VRK1重組蛋白
貨號：

CSB-EP655594BO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

牛VRK1重組蛋白
貨號：

CSB-EP655594BO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

牛VRK1重組蛋白
貨號：

CSB-BP655594BO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

牛VRK1重組蛋白
貨號：

CSB-MP655594BO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

VRK1
Uniprot No.：

Q32PI1
別名：

VRK1Serine/threonine-protein kinase VRK1; EC 2.7.11.1; Vaccinia-related kinase 1
種屬：

Bos taurus (Bovine)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-396
氨基酸序列

MPRVKAAQAG RQGPAKRRLA EHFAAGEIIT DMNKKEWKLG SPIGQGGFGC IYLADMNSSK SVGNDAPCVV KVEPSDNGPL FTELKFYQRA AKPEQIQKWI RTHKLKYLGV PKYWGSGLHD KNGKSYRFMI IDRFGSDLQK IYEANAKRFS RKTVLQLSLR ILDILEYIHE HEYVHGDIKA SNLLLSYKNP DQVYLVDYGL AYRYCPEGTH KEYKEDPKRC HDGTVEFTSI DAHNGVAPSR RGDLEILGYC MIQWLSGHLP WEDNLKDPNY VRDSKIRYRE NIASLMDKCF PEKNKPDEIA KYMETVKLLD YVEKPLYQKL RDILLQGLKA IGSKDDGKLD LTVVENGSLK AKPVAKKRKK EAEESVESSV EDMECSDKQT EEATQTRSKT RKRVQK
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity.
亞細(xì)胞定位：

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle.
蛋白家族：

Protein kinase superfamily, CK1 Ser/Thr protein kinase family, VRK subfamily
數(shù)據(jù)庫鏈接：

KEGG: bta:618880

UniGene: Bt.11497