Recombinant Bovine Inhibitor of growth protein 4 (ING4)

中文名稱：

牛ING4重組蛋白
貨號：

CSB-YP668816BO
規格：
來源：

Yeast
其他：

中文名稱：

牛ING4重組蛋白
貨號：

CSB-EP668816BO
規格：
來源：

E.coli
其他：

中文名稱：

牛ING4重組蛋白
貨號：

CSB-EP668816BO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

牛ING4重組蛋白
貨號：

CSB-BP668816BO
規格：
來源：

Baculovirus
其他：

中文名稱：

牛ING4重組蛋白
貨號：

CSB-MP668816BO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ING4
Uniprot No.：

Q3T095
別名：

ING4; Inhibitor of growth protein 4; p29ING4
種屬：

Bos taurus (Bovine)
蛋白長度：

full length protein
表達區域：

1-248
氨基酸序列

MAAGMYLEHY LDSIENLPFE LQRNFQLMRD LDQRTEDLKA EIDKLASEYM SSARSRSSEE KLALLRQIQE AYGKCKEFGD DKVQLAMQTY EMVDKHIRRL DTDLARFEAD LKEKQIESSD YDSSSSKGKK SRTQKEKKAA RARSKGKNSD EEAPKAAQKK LKLVRTSPEY GMPSVTFGSV HPSDVLDMPV DPNEPTYCLC HQVSYGEMIG CDNPDCSIER FHFACVGLTT KPRGKWFCPR CSQERKKK
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). Can enhance apoptosis induced by serum starvation in mammary epithelial cell line HC11.
亞細胞定位：

Nucleus.
蛋白家族：

ING family
數據庫鏈接：

KEGG: bta:532483

STRING: 9913.ENSBTAP00000022686

UniGene: Bt.48844