Recombinant Arabidopsis thaliana Glutamate decarboxylase 1 (GAD1), partial

中文名稱：

擬南芥GAD1重組蛋白
貨號：

CSB-YP677079DOA
規(guī)格：
來源：

Yeast
其他：

中文名稱：

擬南芥GAD1重組蛋白
貨號：

CSB-EP677079DOA
規(guī)格：
來源：

E.coli
其他：

中文名稱：

擬南芥GAD1重組蛋白
貨號：

CSB-EP677079DOA-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

擬南芥GAD1重組蛋白
貨號：

CSB-BP677079DOA
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

擬南芥GAD1重組蛋白
貨號：

CSB-MP677079DOA
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

GAD1
Uniprot No.：

Q42521
別名：

GAD1; GAD; GDH1; At5g17330; MKP11.30; MKP11_18Glutamate decarboxylase 1; GAD 1; EC 4.1.1.15
種屬：

Arabidopsis thaliana (Mouse-ear cress)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Catalyzes the production of GABA. The calmodulin-binding is calcium-dependent and it is proposed that this may, directly or indirectly, form a calcium regulated control of GABA biosynthesis.
基因功能參考文獻：
1. mutations in the two lobes affect GAD1 activation in similar ways and only intact AtCaM1 can fully activate GAD1. Taken together, our data provide new insights into the CaM lobes role in interactions between CaM and plant GAD. PMID: 26708477
2. Insertion mutants of GAD1 revealed that GABA levels in roots were drastically reduced compared with those in the wild type. PMID: 15604684
3. Antibody titers to this enzyme identify two subgroups of patients with adult-onset autoimmune diabetes having distinct clinical, autoimmune, and genetic features. PMID: 17392553
4. Calmodulin activates Gad1 in a unique way by relieving two C-terminal autoinhibition domains of adjacent active sites, forming a 393 kDa Gad1-calmodulin complex with an unusual 1:3 stoichiometry. PMID: 19580813
蛋白家族：

Group II decarboxylase family
組織特異性：

Expressed in roots. Detected at low levels in shoots of young seedlings. Not detected in the root tips or in the central vascular bundle in the elongating region of mature roots.
數(shù)據(jù)庫鏈接：

KEGG: ath:AT5G17330

STRING: 3702.AT5G17330.1

UniGene: At.25228