The Binding Activity of CCHFV GP with Anti-GP recombinant antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized CCHFV GP (CSB-MP810349CSC2) at 2 μg/mL can bind Anti-GP recombinant antibody. The EC50 is 3.136-3.585 ng/mL.
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貨期:
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用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Glycoprotein C and glycoprotein N interact with each other and are present at the surface of the virion. They are able to attach the virion to host cell receptors. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Also promotes fusion of viral membrane with host endosomal membrane after endocytosis of the virion.
亞細胞定位:
[Glycoprotein C]: Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein.; [Glycoprotein N]: Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein.