欧美最新另类人妖I国产成人av一区二区三区在线观看I九九热精品视频在线观看I国产精品日韩在线I激情av五月婷婷I日韩精品免费

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 重組抗體
  4. GNB2 Recombinant Monoclonal Antibody

GNB2 Recombinant Monoclonal Antibody

  • 中文名稱：
    GNB2 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA124843A0HU
  • 規格：
    ￥1320
  • 圖片：
    • Flow cytometric analysis of G protein subunit beta 2 expression in HT-1080 cells using G protein subunit beta 2 antibody. Green, isotype control; red, G protein subunit beta 2.
    • Immunocytochemical staining of HT-1080 cells with G protein subunit beta 2 antibody. Nuclei were stained blue with DAPI; G protein subunit beta 2 was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.
    • Western blotting analysis using G protein subunit beta 2 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with G protein subunit beta 2 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    GNB2; Transducin Beta Chain 2; Signal-Transducing Guanine Nucleotide-Binding Regulatory Protein Beta Subunit 2; Guanine Nucleotide Binding Protein (G Protein), Beta Polypeptide 2; Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Beta Subunit 2; Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Subunit Beta-2; G Protein, Beta-2 Subunit; G Protein Subunit Beta-2; Heterotrimeric Guanine Nucleotide-Binding Protein 2C1; Epididymis Secretory Sperm Binding Protein; SSS4; NEDHYDF; HG2C1;SSS4
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human GNB2 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    1A12
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, FC, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    FC 1:200-1:2000
    ICC 1:100-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
  • 基因功能參考文獻：
    1. A GNB2 gene mutation is associated with familial sinus node and atrioventricular conduction dysfunction. PMID: 28219978
    2. MIF and GNbeta2 interacted with influenza A H1N1 virus PB1-F2 protein. PMID: 23043599
    3. Results indicate that G protein beta2 (Gbeta2) is required for starvation-induced NF-kappaB activation and constitutive NF-kappaB activity. PMID: 22917497
    4. We conclude that the Gbetagamma complex interacts with the GR and suppresses its transcriptional activity by associating with the transcriptional complex formed on GR-responsive promoters. PMID: 15955845
    5. Recombinant Gbetagamma subunits were used to establish that the Gbeta(2)gamma(2) dimer can selectively reconstitute the inhibition of alpha(1H) channels in isolated membrane patches. PMID: 16973746

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, perinuclear region.
  • 蛋白家族：
    WD repeat G protein beta family
  • 數據庫鏈接：

    HGNC: 4398

    OMIM: 139390

    KEGG: hsa:2783

    STRING: 9606.ENSP00000305260

    UniGene: Hs.185172



×
生命科學計算平臺