SLC25A3 Antibody

說(shuō)明書(shū)

產(chǎn)品詳情

Uniprot No.：

Q00325
基因名：

SLC25A3
別名：

mitochondrial antibody; Mitochondrial phosphate carrier protein antibody; MPCP_HUMAN antibody; OK/SW cl.48 antibody; PHC antibody; Phosphate carrier protein antibody; Phosphate carrier protein mitochondrial antibody; Phosphate carrier protein mitochondrial precursor antibody; Phosphate transport protein antibody; PTP antibody; Slc25a3 antibody; Solute carrier family 25 member 3 antibody; Solute carrier family 25 mitochondrial carrier phosphate carrier member 3 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Human SLC25A3
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,IHC
Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochondrial permeability transition pore (mPTP).
基因功能參考文獻(xiàn)：
1. these results indicate that PiC depletion may need to be profound (>85%) to substantially affect maximal oxphos and that pathogenesis associated with PiC depletion or loss of function may be independent of phosphate limitation when ATP requirements are not high. PMID: 27780865
2. Compares and contrasts all the known human SLC25A* genes and includes functional information. PMID: 23266187
3. An analysis of the promoter region of the human mitochondrial phosphate transporter, including its activation and inhibition domains, is reported. PMID: 15984930
4. SLC25A3 protein deficiency is associated with lactic acidosis, hypertrophic cardiomyopathy, and muscular hypotonia PMID: 17273968
相關(guān)疾?。?/div>
Mitochondrial phosphate carrier deficiency (MPCD)
亞細(xì)胞定位：

Mitochondrion inner membrane; Multi-pass membrane protein.
蛋白家族：

Mitochondrial carrier (TC 2.A.29) family
數(shù)據(jù)庫(kù)鏈接：

HGNC: 10989

OMIM: 600370

KEGG: hsa:5250

STRING: 9606.ENSP00000228318

UniGene: Hs.290404