MEIS3 Antibody, Biotin conjugated

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) MEIS3 Polyclonal antibody
Uniprot No.：

Q99687
基因名：

MEIS3
別名：

Homeobox protein meis3 antibody; Meis homeobox 3 antibody; Meis1 myeloid ecotropic viral integration site 1 homolog 3 antibody; Meis1 related protein 2 antibody; Meis1-related protein 2 antibody; meis3 antibody; MEIS3_HUMAN antibody; MRG2 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Homeobox protein Meis3 protein (178-264AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells. Also regulates expression of NDFIP1, BNIP3, and CCNG1.
基因功能參考文獻：
1. Findings support a model in which Meis3 is required for neural crest proliferation, migration into, and colonization of the gut such that its loss leads to severe defects in enteric nervous system development. PMID: 26354419
2. This work suggests that the transcriptional activity of all members of the Meis/Prep Hth protein family is subject to autoinhibition by their Hth domains, and that the Meis3.2 splice variant encodes a protein that bypasses this autoinhibitory effect. PMID: 20553494
亞細胞定位：

Nucleus.
蛋白家族：

TALE/MEIS homeobox family
數據庫鏈接：

HGNC: 29537

KEGG: hsa:56917

UniGene: Hs.356135