DHTKD1 Antibody

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) DHTKD1 Polyclonal antibody
Uniprot No.：

Q96HY7
基因名：

DHTKD1
別名：

AMOXAD antibody; CMT2Q antibody; Dehydrogenase E1 and transketolase domain containing 1 antibody; Dehydrogenase E1 and transketolase domain containing protein 1 antibody; Dehydrogenase E1 and transketolase domain-containing protein 1 antibody; DHTK1_HUMAN antibody; dhtkd1 antibody; DKFZp762M115 antibody; KIAA1630 antibody; MGC3090 antibody; Probable 2 oxoglutarate dehydrogenase E1 component DHKTD1 mitochondrial antibody; Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1; mitochondrial antibody
宿主：

Rabbit
反應(yīng)種屬：

Human, Mouse
免疫原：

Recombinant Human Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial protein (1-280AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
基因功能參考文獻：
1. DHTKD1 encodes the E1 subunit of the alpha-ketoadipic acid dehydrogenase complex PMID: 25860818
2. DHTKD1 contributes to mitochondrial biogenesis and function maintenance. PMID: 24076469
3. DHTKD1 mutations cause 2-aminoadipic and 2-oxoadipic aciduria. PMID: 23141293
4. A nonsense mutation in DHTKD1 causes Charcot-Marie-Tooth disease type 2 in a large Chinese pedigree. PMID: 23141294
相關(guān)疾病：

Charcot-Marie-Tooth disease 2Q (CMT2Q); 2-aminoadipic 2-oxoadipic aciduria (AMOXAD)
亞細(xì)胞定位：

Mitochondrion.
蛋白家族：

Alpha-ketoglutarate dehydrogenase family
數(shù)據(jù)庫鏈接：

HGNC: 23537

OMIM: 204750

KEGG: hsa:55526

STRING: 9606.ENSP00000263035

UniGene: Hs.104980