AP1S1 Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) AP1S1 Polyclonal antibody
Uniprot No.：

P61966
基因名：

AP1S1
別名：

Adapter related protein complex 1 sigma 1A subunit antibody; Adapter-related protein complex 1 sigma-1A subunit antibody; Adaptor protein complex AP-1 sigma-1A subunit antibody; Adaptor protein complex AP1 sigma 1A subunit antibody; AP-1 complex subunit sigma-1A antibody; AP1 complex subunit sigma 1A antibody; AP19 antibody; AP1S1 antibody; AP1S1_HUMAN antibody; CLAPS1 antibody; Clathrin assembly protein complex 1 sigma 1A small chain antibody; Clathrin assembly protein complex 1 sigma-1A small chain antibody; Clathrin coat assembly protein AP19 antibody; Golgi adaptor HA1/AP1 adaptin sigma 1A subunit antibody; Golgi adaptor HA1/AP1 adaptin sigma-1A subunit antibody; HA1 19 kDa subunit antibody; Sigma 1a subunit of AP-1 clathrin antibody; Sigma 1a subunit of AP1 clathrin antibody; Sigma adaptin 1A antibody; Sigma-adaptin 1A antibody; Sigma1A adaptin antibody; Sigma1A-adaptin antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human AP-1 complex subunit sigma-1A protein (1-127AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，AP1S1 Antibody (CSB-PA001866LA01HU)，的標記方式是Non-conjugated。對于AP1S1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA001866LB01HU	AP1S1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA001866LC01HU	AP1S1 Antibody, FITC conjugated
Biotin	CSB-PA001866LD01HU	AP1S1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
基因功能參考文獻：
1. We solved the pathogenetic mechanism of MEDNIK syndrome, demonstrating that AP1S1 regulates intracellular copper machinery mediated by copper-pump proteins PMID: 23423674
2. A splice mutation in AP1S1 was found in four families with a neurocutaneous syndrome. PMID: 19057675
3. Isolation and description of the rat and mouse genes. PMID: 2040623
相關疾病：

Mental retardation, enteropathy, deafness, peripheral neuropathy, ichthyosis, and keratoderma (MEDNIK)
亞細胞定位：

Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
蛋白家族：

Adaptor complexes small subunit family
組織特異性：

Widely expressed.
數據庫鏈接：

HGNC: 559

OMIM: 603531

KEGG: hsa:1174

STRING: 9606.ENSP00000336666

UniGene: Hs.489365