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Rat macrophage inflammatory protein 1β,MIP-1β ELISA kit

  • 中文名稱:
    大鼠巨噬細胞炎癥蛋白1β(MIP-1β/CCL4)酶聯免疫試劑盒
  • 貨號:
    CSB-E07421r
  • 規格:
    96T/48T
  • 價格:
    ¥3600/¥2500
  • 促銷:
  • 其他:

產品詳情

  • 產品描述:
    大鼠巨噬細胞炎癥蛋白1β(MIP-1β/CCL4)酶聯免疫試劑盒(CSB-E07421r)為雙抗夾心法ELISA試劑盒,定量檢測血清血漿組織裂解液不稀釋樣本中的CCL4含量。CCL4即趨化因子配體4,在免疫調節等生理過程中起重要作用。其背景與免疫細胞的招募和活化密切相關。研究機制上,CCL4通過與相應受體結合,引導免疫細胞遷移、調控免疫反應,在炎癥、腫瘤等疾病病理進程中有相關研究。試劑盒檢測范圍為3.9pg/ml-250pg/ml,適用于炎癥相關動物模型構建、免疫調控機制解析、藥理學研究中生物標志物動態監測等科研場景,為研究者探索巨噬細胞活化、趨化因子網絡交互作用等基礎研究提供可靠工具本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
  • 別名:
    Ccl4 ELISA Kit; Mip1b ELISA Kit; Scya4C-C motif chemokine 4 ELISA Kit; Macrophage inflammatory protein 1-beta ELISA Kit; MIP-1-beta ELISA Kit; Small-inducible cytokine A4 ELISA Kit
  • 縮寫:
  • Uniprot No.:
  • 種屬:
    Rattus norvegicus (Rat)
  • 反應時間:
    1-5h
  • 上樣量:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領域:
    Immunology
  • 測定原理:
    quantitative
  • 測定方法:
    Sandwich
  • 精密度:

  • 線性度:

  • 回收率:

  • 標準曲線:

  • 數據處理:
  • 貨期:
    3-5 working days

產品評價

靶點詳情

  • 功能:
    Monokine with inflammatory and chemokinetic properties.
  • 基因功能參考文獻:
    1. Tong Luo Jiu Nao injection inhibits MIP-1beta expression in brain microvascular endothelial cells injured by oxygen-glucose deprivation and inhibitors microglial cell proliferation. PMID: 22366434
    2. Early and persistent up-regulation of CCL4/CCR5 signaling during epileptogenesis suggests that CCL4 signaling, rather than CCL2 signaling, could have a role in the epileptogenic process. PMID: 22353418
    3. this study we present data on long term increase in CCL4 mRNA expression and immunoreactivity following epileptogenic stimulus in a rat model of temporal lobe epilepsy. PMID: 21731074
    4. During experimental allergic encephalomyelitis, a strong activation of spinal perivascular macrophages is observed accompanied by a consistently increased expression of MIP-1 alpha. PMID: 12196270
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Intercrine beta (chemokine CC) family
  • 數據庫鏈接:


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