Rat macrophage inflammatory protein 1β,MIP-1β ELISA kit
產品詳情
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產品描述:大鼠巨噬細胞炎癥蛋白1β(MIP-1β/CCL4)酶聯免疫試劑盒(CSB-E07421r)為雙抗夾心法ELISA試劑盒,定量檢測血清血漿組織裂解液不稀釋樣本中的CCL4含量。CCL4即趨化因子配體4,在免疫調節等生理過程中起重要作用。其背景與免疫細胞的招募和活化密切相關。研究機制上,CCL4通過與相應受體結合,引導免疫細胞遷移、調控免疫反應,在炎癥、腫瘤等疾病病理進程中有相關研究。試劑盒檢測范圍為3.9pg/ml-250pg/ml,適用于炎癥相關動物模型構建、免疫調控機制解析、藥理學研究中生物標志物動態監測等科研場景,為研究者探索巨噬細胞活化、趨化因子網絡交互作用等基礎研究提供可靠工具本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
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別名:Ccl4 ELISA Kit; Mip1b ELISA Kit; Scya4C-C motif chemokine 4 ELISA Kit; Macrophage inflammatory protein 1-beta ELISA Kit; MIP-1-beta ELISA Kit; Small-inducible cytokine A4 ELISA Kit
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縮寫:
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Uniprot No.:
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種屬:Rattus norvegicus (Rat)
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反應時間:1-5h
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上樣量:50-100ul
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檢測波長:450 nm
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研究領域:Immunology
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測定原理:quantitative
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測定方法:Sandwich
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精密度:
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線性度:
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回收率:
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標準曲線:
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數據處理:
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貨期:3-5 working days
相關產品
靶點詳情
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功能:Monokine with inflammatory and chemokinetic properties.
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基因功能參考文獻:
- Tong Luo Jiu Nao injection inhibits MIP-1beta expression in brain microvascular endothelial cells injured by oxygen-glucose deprivation and inhibitors microglial cell proliferation. PMID: 22366434
- Early and persistent up-regulation of CCL4/CCR5 signaling during epileptogenesis suggests that CCL4 signaling, rather than CCL2 signaling, could have a role in the epileptogenic process. PMID: 22353418
- this study we present data on long term increase in CCL4 mRNA expression and immunoreactivity following epileptogenic stimulus in a rat model of temporal lobe epilepsy. PMID: 21731074
- During experimental allergic encephalomyelitis, a strong activation of spinal perivascular macrophages is observed accompanied by a consistently increased expression of MIP-1 alpha. PMID: 12196270
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亞細胞定位:Secreted.
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蛋白家族:Intercrine beta (chemokine CC) family
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數據庫鏈接:
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